Active — Not RecruitingNot Applicable

Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients

United States350 participantsStarted 2014-02

Plain-language summary

The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Enrolled in the original ORARAD study * Willing to participate and comply with all study procedures Exclusion Criteria: * Anything that would place the participant at increased risk or preclude the participant's full compliance with or completion of the study (e.g., unable to obtain consent or unable to tolerate an oral examination).

What they're measuring

Dental Caries

Timeframe: 7 years

Bleeding on probing is documented (yes/no) (Periodontal Measure 1)

Timeframe: 7 years

Clinical attachment loss (CAL) (Periodontal Measure 2)

Timeframe: 7 years

Pocket depth (Periodontal Measure 3)

Timeframe: 7 years

Tooth Loss

Timeframe: 7 years

Exposed intraoral bone

Timeframe: 7 years

Salivary flow

Timeframe: 7 years

Trial details

NCT IDNCT05325970

SponsorWake Forest University Health Sciences

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06

View on ClinicalTrials.gov More Head and Neck Cancer trials