Not Yet RecruitingNot Applicable

Urinary Continence of Female POPRC and OIN

China58 participantsStarted 2022-04

Plain-language summary

To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.

Who can participate

Age range55 Years – 75 Years

SexFEMALE

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Inclusion criteria

✓. Female patients aged between 55-75.
✓. Patients those who are diagnosed with organ-confined urothelial carcinoma（\<pT3）
✓. Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.
✓. ECOG score between 0-2;
✓. Normal renal function;
✓. Patients those who volunteer to participate in this study and sign the informed consents.
✓. Patients those who are able to cooperate in the study.

Exclusion criteria

✕. Absence of tumour in bladder neck or urethra;
✕. Patients thsoe who are diagnosed distant metastasis before surgery.
✕. Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;
✕. Patients those who are diagnosed with other malignancies.;
✕. Patients those who had received pelvic radiotherapy or major pelvic operation.
✕. Pregnancy status;
✕. Any other conditions that the researcher considers to be excluded from this study

What they're measuring

day-time and night-time continence rate

Timeframe: 6 months

Trial details

NCT IDNCT05325216

SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-04-01

Contact for this trial

Wenlong Zhong, MD

86-18510904167 zhongwlong3@mail.sysu.edu.cn

View on ClinicalTrials.gov More Urinary Bladder Neoplasms trials