UnknownNot Applicable

Lp(a) With CCTA Assessed Parameters and Clinical Outcomes

China378 participantsStarted 2016-03-20

Plain-language summary

Lipoprotein(a) \[Lp(a)\] is a risk factor for cardiovascular events, although the underlying mechanism remains unclear. This study evaluated the relationship between Lp(a) and high-risk attributes (HRA) by coronary computed tomography angiography (CCTA) as well as their prognostic value.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with Lp(a) meaured within 1 week of CCTA examination. Exclusion Criteria: * unstable angina pectoris * acute myocardial infarction * New York Heart Association class III-IV heart failure * with a history of bypass surgery * active infection * respiratory failure * chronic kidney disease (estimated glomerular filtration rate \[eGFR\] \<60 ml/min/1.73 m2) * liver dysfunction (liver enzyme \>3 upper reference limit \[URL\] or bilirubin \>2 URL) * malignancy * systemic connective tissue disease * poor CCTA imaging quality not suitable for analysis * other situations not suitable for the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Major adverse cardiac events

Timeframe: at 24 months from index procedure

Trial details

NCT IDNCT05323227

SponsorShanghai Zhongshan Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-04-30

Contact for this trial

Neng Dai, MD

+8613701997266 niceday1987@hotmail.com

View on ClinicalTrials.gov More Coronary Artery Disease trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Association of Lp(a) level with CCTA measured Parameters

Timeframe: at the index procedure

Major adverse cardiac events

Timeframe: at 24 months from index procedure