Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis (NCT05322421) | Clinical Trial Compass
CompletedNot Applicable
Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis
Egypt20 participantsStarted 2022-01-10
Plain-language summary
This research aims to investigate the effectiveness of topical olive oil application both clinically and biochemically as a suitable affordable treatment modality for prevention and management of radiation oral mucositis and its associated pain for head and neck cancer patients receiving radiotherapy.
Who can participate
Age range
25 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients who are aged above 25 years up to 65 years.
* Both genders are eligible.
* Patients with head and neck cancer who are planned to receive radiotherapy either as postoperative (adjuvant after surgery) or definitive therapy.
* Patients planned to receive radiotherapy treatment with a dose of 60-70 Gy.
Exclusion Criteria:
* Patients with known sensitivity to olive oil and/or any of its products
* Patients with gingival or oral ulceration or mucositis
* Smokers
* Vulnerable patients (pregnant women, neonates, children, prisoners, persons with physical handicaps or mental disabilities)
* Pregnant and lactating women.
* Patients with any uncontrolled systemic diseases (such as diabetes, cardiovascular, liver disorder, renal dysfunction)
* Patients suffering from any physical or mental disabilities that would interfere with or be affected by the study procedure.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Oral Radiation mucositis
Timeframe: Every other week ( 2 weeks, 4 weeks and 6 at the end of the treatment)
2
Grade of oral radiation mucositis
Timeframe: Every other week ( 2 weeks, 4 weeks and 6 weeks at the end of the treatment)