Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM) (NCT05320887) | Clinical Trial Compass
CompletedNot Applicable
Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
United States69 participantsStarted 2022-07-27
Plain-language summary
This study is proposing a four condition Electronic Tobacco Marketplace (ETM) study to determine if banning normal nicotine content (NNC) is sufficient for encouraging smokers to switch to potentially less harmful products or if the availability of higher nicotine and/or flavored alternative products (specifically e-cigarettes) are needed to achieve maximal reductions in smoking.
Who can participate
Age range
21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 21+ years of age
* Self-report smoking at least 5 cigarettes per day for the past year
* Breathe carbon monoxide (CO) level \> 8 ppm or positive urine NicCheck
* Willingness to use other tobacco products during the study
* Speak, comprehend, and read English sufficiently to complete study procedures
* Have home access to a computer, smart phone, or tablet with a web camera and internet access
* Tried a vaping device at least once in their lifetime
Exclusion Criteria:
* Currently seeking treatment to quit smoking
* Self-reported serious medical or psychiatric condition(s) including cardiovascular and chronic respiratory diseases
* Body temperature \> 100.4 F
* Cold, flu or COVID-19 symptoms including fever, cough, and runny nose in the past 30 days
* Currently pregnant, breastfeeding or intending to become pregnant for the duration of the study or unwilling to agree to use adequate protection to avoid pregnancy
* CO reading \> 80 ppm
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Cigarettes Purchased
Timeframe: Visit 6 approximately 4 weeks after baseline