Diagnosis and Bacterial Identification of Periprosthetic Joint Infection With Microbial-ID

Inclusion Criteria: * Patient has complaints (pain, stiffness) about the prosthetic joint And has clinical features for joint infection at physical examination (swelling, redness, warm, sinus tract) AND has an elevated serum CRP (\>10 mg/L) * Patient is scheduled for a puncture AND/OR surgery, with harvesting of synovial fluid * Patient ≥ 18 years of age * Patient is competent, able, and willing to provide written informed consent Exclusion Criteria: * Treatment with antibiotics ≤2 weeks prior to puncture and/or surgery; * Other obvious reason(s) for implant dysfunction, such as: fracture, an implant breakage, a malposition, and/or a tumour.