A Study of the Use of Acellular Dermal Matrix for Breast Reconstruction

Inclusion Criteria: * Females aged 21-60 years * Planning to undergo unilateral or bilateral mastectomy, prophylactically or to treat breast cancer * Planning to undergo immediate two-stage prosthetic breast reconstruction with TE placement as the first stage * Planning to undergo nipple-sparing or skin-sparing mastectomy * Adequate mastectomy skin perfusion or adequate perfusion but nonviable mastectomy skin that can be excised (≤4 cm) at the defect margins with otherwise adequate perfusion * Intraoperative confirmation of prepectoral plane viability by operating physician Exclusion Criteria: * History of radiotherapy to the operative breast * Current smoker * Non-English speaking patients * Planning to undergo direct-to-implant reconstruction * Prior sternotomy