CompletedNot Applicable

Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.

United States137 participantsStarted 2021-10-01

Plain-language summary

The ZTWINS registry study is an observational, prospective, multi-center study observing women carrying a twin pregnancy who receive snp-based non-invasive prenatal screening and zygosity assessment as part of their medical care.

Who can participate

Age range18 Years – 55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women with an ultrasound confirmation of twin pregnancy Exclusion Criteria: * Singleton or non-twin multiple pregnancy

What they're measuring

Assess clinical utility of combining NIPT-based zygosity measurements with ultrasound chorionicity assessments for the management of twin pregnancies.

Timeframe: 2 years

Frequency of monozygosity

Timeframe: 2 years

Frequency of changed chorionicity assessment

Timeframe: 2 years

Frequency of late TTTS diagnosis

Timeframe: 2 years

Trial details

NCT IDNCT05312814

SponsorNatera, Inc.

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2023-05-15

View on ClinicalTrials.gov More Twin to Twin Transfusion Syndrome trials