Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

Inclusion Criteria: Down Syndrome CAVSD Repair Group: * Trisomy 21 * Male or Female, ages 5 years through 12 years * Had CAVSD repair within the first year of life * Parent or guardian and patient willing to comply with protocol and complete all study assessments; parent or guardian willing to provide written informed consent * Child able to speak and understand English Down Syndrome Comparison Group * Trisomy 21 * Male or Female, age 5 years through 12 years * No major CHD, defined as CHD requiring previous or planned CHD surgery * Parent or guardian and patient willing to comply with protocol and complete all study assessments; parent or guardian willing to provide written informed consent * Child able to speak and understand English Exclusion Criteria: Both Groups \- Mosaic DS Down Syndrome CAVSD Repair Group only - Did not have CAVSD repair in the first year of life Down Syndrome Comparison Group only \- Major CHD requiring previous or planned CHD surgery - i.e., CHD surgery occurring (a) in the period between birth and time of recruitment into the CHILD-DS Study, or (b) planned for a future date.