CompletedNot Applicable

Multiple Sclerosis and Overactive Bladder Treatment

Turkey (Türkiye)16 participantsStarted 2021-06-08

Plain-language summary

Urinary symptoms are frequently seen in patients with Multiple Sclerosis (MS). Early evaluation of the patients in terms of the urinary system, planning the appropriate treatment and following up at regular intervals are extremely important in terms of preventing urinary system complications. Neuromodulation applications are used reliably in the urological treatment of MS patients. The aim of this study was to compare the efficacy of different neuromodulation techniques, transcutaneous posterior tibial nerve stimulation and repetitive transcranial magnetic stimulation, in patients with MS reporting lower urinary tract symptoms.

Who can participate

Age range

18 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-65 years old * Woman * Volunteer to participate in the study * Neurogenic overactive bladder due to MS * EDSS \<7.0 * Not benefiting from pharmacological treatment Exclusion Criteria: * With urinary tract infection * Diagnosed with diabetes mellitus * Using diuretic medication * Using clean intermittent catheterization * Having a history of different urological diseases * Those who have conditions that would be contraindicated for electrical stimulation (pacemaker, brain pacemaker, prosthesis)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Urodynamics Test

Timeframe: "10 days" the amount of change after 10 days from the baseline

Extended Disability Status Scale (EDSS)

Timeframe: "10 days" the amount of change after 10 days from the baseline

Overactive Bladder Questionnaire-V8 (OAB-V8)

Timeframe: "10 days" the amount of change after 10 days from the baseline

Incontinence Quality of Life -I-QOL

Timeframe: "10 days" the amount of change after 10 days from the baseline

Voiding Diary

Timeframe: "10 days" the amount of change after 10 days from the baseline

Incontinence Severity Index (ISI)

Timeframe: "10 days" the amount of change after 10 days from the baseline

Trial details

NCT IDNCT05312138

SponsorIstanbul Medipol University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-08

View on ClinicalTrials.gov More Neurogenic Bladder Dysfunction trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Urodynamics Test

Timeframe: "10 days" the amount of change after 10 days from the baseline

Extended Disability Status Scale (EDSS)

Timeframe: "10 days" the amount of change after 10 days from the baseline

Overactive Bladder Questionnaire-V8 (OAB-V8)

Timeframe: "10 days" the amount of change after 10 days from the baseline

Incontinence Quality of Life -I-QOL

Timeframe: "10 days" the amount of change after 10 days from the baseline

Voiding Diary

Timeframe: "10 days" the amount of change after 10 days from the baseline

Incontinence Severity Index (ISI)

Timeframe: "10 days" the amount of change after 10 days from the baseline