CompletedPhase 2/3

Effectiveness of Vitamin C Supplementation in Treatment of Rickets

Egypt88 participantsStarted 2022-03-01

Plain-language summary

Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C supplementation on bone turnover infants and children with nutritional rickets.

Who can participate

Age range6 Months – 3 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Clinical diagnosis: * Nutritional rickets in infants or children between 6 months and 3 years. * Normal liver and kidney functions. * The parents must be compliant to the clinic visits and the treatment doses. Exclusion Criteria: * Unwilling to participate in the study. * Non nutritional causes of rickets as hypoparathyroidism, renal causes, chronic liver disease, and malabsorption. * Children on vitamin C supplements above RDA.

What they're measuring

Effectiveness of therapeutic doses of vitamin C in clinical finding of rickets

Timeframe: After 1 month stating the trial

Effectiveness of therapeutic doses of vitamin C on anthropometric measures clinical finding of rickets

Timeframe: After 1 month stating the trial

Effectiveness of therapeutic doses of vitamin C in clinical signs of rickets

Timeframe: After 1 month stating the trial

Laboratory follow up of rachitic children and infants

Timeframe: after 1 month from stating the trial

Radiological assessment after treatment for bone healing

Timeframe: after 1 month from stating the trial

Trial details

NCT IDNCT05310760

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-01

View on ClinicalTrials.gov More Nutritional Rickets trials