CompletedNot Applicable

Effect of Muscle Fatigue on Spinal Imbalance and Motion in Lumbar Spinal Stenosis

Switzerland30 participantsStarted 2021-11-11

Plain-language summary

This study assesses spinal imbalance and motion in patients with sLSS and elicits fatigue via back exercises and compares spinal imbalance and motion before and after the fatigue exercise and compares these to healthy controls, allowing to associate sLSS-specific motion patterns to paraspinal muscle fatigue.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria:for patients with sLSS * age \> 30 years * BMI \< 35kg/m2 * diagnosed symptomatic lumbar spinal stenosis * clinical symptoms for at least 6 months * intermittent neurogenic claudication with limitations of their walking ability due to symptoms in the lower back and or in one or both legs * unsuccessful conservative treatment * confirmation of the LSS through MRI * Inclusion criteria for age-matched healthy control subjects * age \> 30 years * BMI \< 35kg/m2 * Inclusion criteria for young healthy control subjects * 18 years ≤ age ≤ 30 years * BMI \< 35kg/m2 Exclusion Criteria:for patients with sLSS * inability to provide informed consent * previous spine surgery * use of walking aids * other neurologic disorders affecting gait * MRI incompatibility * Exclusion criteria for age-matched healthy control subjects * inability to provide informed consent * previous spine surgery * history of claudications * use of walking aids * other neurological or orthopaedic conditions that may affect gait * MRI incompatibility * Exclusion criteria for young healthy control subjects * inability to provide informed consent * previous back injury; previous spine surgery * use of walking aids * current injury of any kind

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Global spinal imbalance assessed using motion capture

Timeframe: approximate duration: 30 minutes at baseline and at 1 year after decompression surgery for patients with sLSS

Trial details

NCT IDNCT05309447

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-05-30

View on ClinicalTrials.gov More Lumbar Spinal Stenosis trials