Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial

Inclusion Criteria: * Female * 18 years old or greater * Diagnosis of overactive bladder (urinary urgency or frequency, OAB) or urinary urgency incontinence (UUI) Exclusion Criteria: * Have a diagnosis of neurogenic bladder * Received intravesical botox injections within prior 6 months * Current treatment with either: SNM, PTNS, or OAB medications - need wash out as below * SNM - turn device off for at least 2 weeks prior to procedure, off during 3-month follow up window * PTNS - no treatments within 2 weeks of start, none during 3-month post-procedure follow up window * OAB meds - 2 week wash out period prior to injection, none during 3-month post-procedure follow up window * Currently pregnant or trying to get pregnant * Contraindications to Botox® - hypersensitivity to Botox®, inability to self-catheterize/refusal to have indwelling catheter * Have a UTI (can enroll after treatment) * Have urinary retention (PVR\>150cc on two occasions) * Do not speak English or Spanish