Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants

Inclusion Criteria: * • Patients aged 18 to 50 years * Both male and female patients * Periodontally healthy teeth as determined by Periodontal Probing * Patients with non-vital necrotic pulps as determined by Cold Test * Patients with acute apical periodontitis determined by history and clinical examination * Clinical Findings: Visual: Carious tooth decay Occlusion: Hyperocclusion Pulp vitality test: Negative Periapical radiograph: Caries involving pulp space and PDL widening Percussion Test: Positive Palpation Test: Negative • Single rooted teeth as determined radiographically Exclusion Criteria: * • Multirooted teeth * Teeth undergoing Re-endo treatments * Teeth with root fractures and/ non restorable determined by clinical and radiographic examination * Patients receiving antibiotic treatment in the past 3 months determined by history * Patient with Diabetes determined by history * Patient with history of smoking