CompletedNot Applicable

Low-grade Inflammation and Gut Symptoms From A2 and Hydrolyzed A1 Milk

Finland37 participantsStarted 2022-05-18

Plain-language summary

The aim of this study is to reveal how different forms of milk casein, lactose and moderate breakdown of proteins affect the symptoms that may arise from milk and markers of inflammation in volunteers receiving symptoms from milk. Research hypotheses are: 1) Protein hydrolyzed milk is as tolerated or better tolerated than A2 milk, and 2) Lactose is the main causative agent of stomach symptoms in milk-sensitive individuals.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Perceive disturbing gut symptoms from regular milk * Commits to the research diet for the whole research period * Age: 18-65 * BMI: 18.5-30 * Healthy (normal kidney, liver and thyroid function and self-reported) Exclusion Criteria: * Milk allergy * Regular medication (other than contraceptives) or medication affecting the gut * Recent course of antibiotics (\< 3 months prior the study) * Pregnancy or lactation * Diagnosed bowel disease

What they're measuring

Changes from baseline in Inflammation marker IL-4

Timeframe: after treatment (4th day)

Trial details

NCT IDNCT05305391

SponsorUniversity of Turku

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-03

View on ClinicalTrials.gov More Milk Intolerance trials