CompletedNot Applicable

Intravenous Fluid Administration's Effect on Pediatric Lumbar Puncture

United States182 participantsStarted 2022-11-22

Plain-language summary

The purpose of this project is to determine if administration of normal saline intravenous fluids prior to a lumbar puncture improves first time success of lumbar puncture in infants less than 3 months of age. First time success of lumbar puncture defined as cerebrospinal fluid obtained on the first attempt with less than 1000 red blood cells per mm3 in the fluid specimen.

Who can participate

Age range0 Months – 3 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ages 0 and 3 months * Patient at Children's of Alabama's Emergency Department * Undergoing a lumbar puncture as part of their clinical work-up Exclusion Criteria: * Vertebral abnormalities * Severe scoliosis * Lumbar puncture to be performed by interventional radiology * Received intravenous fluids prior to study enrollment * Hypotension requiring fluid resuscitation * Shock requiring fluid resuscitation * Ultrasound assistance * Lumbar puncture performed or attempted at another hospital within 24 hours

What they're measuring

Successful Lumbar Puncture

Timeframe: 1 to 1.5 hours

Trial details

NCT IDNCT05302765

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-31

View on ClinicalTrials.gov More Pediatric Lumbar Puncture trials