Semaglutide Use in Elderly Obese Patients (NCT05302596) | Clinical Trial Compass
CompletedPhase 2
Semaglutide Use in Elderly Obese Patients
United States16 participantsStarted 2022-09-01
Plain-language summary
This is a single-center, prospective, controlled, randomized and open label study to investigate the effect of the semaglutide addition to standard of care weight loss intervention (personalized lifestyle and exercise) in elderly obese subjects on body weight and body composition as assessed by DEXA.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Males and females age: ≥65 years
. BMI ≥30 Kg/m2 AND waist circumference for women: \> 80 cm and for men: \> 90 cm
. Stable body weight (no more than ±3 kg change during the 3 months prior to screening)
. Able to participate in personalized physical activities and dietary instructions.
. Participant must be able to read, write, and understand the English language and be able to provide written consent.
Exclusion criteria
. Current diagnosis of weight changing condition including cancer, gastrointestinal conditions or eating disorders
. GLP-1R agonists use within last 6 months
. Diagnosis of type 1 or 2 diabetes
. Impaired cognitive function (VA-St. Louis University Mental Survey (VA-SLUMS) score ≤ 19)
. History of chronic/idiopathic acute pancreatitis
. Personal/family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Body Composition as Total Fat Mass/ Total Fat-free Mass Ratio