Helicobacter Pylori Eradication Therapy for Epileptic Children

Inclusion Criteria: * Age between 4 and 18 years. * Idiopathic generalized epilepsies (IGE), including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy, or IGE with generalized tonic-clonic seizures only (IGE-TCS). * Drug-resistant epilepsy, defined as failure of adequate trials of two tolerated and appropriately chosen and used anti-epileptic drugs schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom * Positive H. pylori stool antigen (HpSA) test (at initial screening). Exclusion Criteria: * Failure to obtain informed consent. * Presence of a medical indication for treating H. pylori infection, including gastric or duodenal ulcer, chronic immune thrombocytopenic purpura, and refractory iron deficiency anemia. * Known allergy or contraindications to any of the study drugs. * Treatment with antibiotics and/or proton pump inhibitors in the last 2 months.