TerminatedNot Applicable

Suture Repair of Lacerations in the ED: Comparison Between Two Suture Materials

Stopped: Study closed due to recruitment problems

United States6 participantsStarted 2022-08-23

Plain-language summary

This study aims to determine whether the use of non-absorbable (i.e. nylon) versus absorbable (i.e. chromic gut) sutures in traumatic hand lacerations affects wound healing, patient perception, and development of complications.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subject seen in PSHMC Emergency Department for hand or forearm lacerations (i.e. laceration below the level of the elbow) that require suture repair, in which Hand Surgery is consulted * CDC surgical wound classification grades I-IV * Age \>18 years of age * Gender: male or female (non-pregnant) * Fluent in written and spoken English * Subject is able to provide voluntary, written informed consent * Subject, in the opinion of the clinical investigator, is able to understand the clinical investigation and is willing to perform all study procedures and follow-up visits * Non-Prisoners Exclusion Criteria: * Known allergy to suture material * History of immunosuppression (i.e. concurrent chemotherapy, steroid use or immunomodulatory therapy) * History of diabetes mellitus * Pregnancy * Current Tobacco use * Age \< 18 years old * Previous skin laceration at same location * History of previous hypertrophic or keloid scar * Concurrent tendon, nerve or bone injury requiring trip to the operating room * Non-English speaking patients * Cognitive impairment * Prisoners

What they're measuring

Score in Wound Healing From Surgery to 2 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 2 weeks post-laceration repair

Score in Wound Healing From Surgery 6 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 6 weeks post-laceration repair

Score in Wound Healing From Surgery 12 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 12 weeks post-laceration repair

Score in Wound Healing From Surgery to 2 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 2 weeks post-laceration repair

Score in Wound Healing From Surgery 6 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 6 weeks post-laceration repair

Score in Wound Healing From Surgery 12 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 12 weeks post-laceration repair

Trial details

NCT IDNCT05281666

SponsorKenneth Taylor, M.D.

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-20

Results submitted2026-02-23

View on ClinicalTrials.gov More Laceration of Hand trials

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Score in Wound Healing From Surgery to 2 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 2 weeks post-laceration repair

Score in Wound Healing From Surgery 6 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 6 weeks post-laceration repair

Score in Wound Healing From Surgery 12 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Patient Portion

Timeframe: 12 weeks post-laceration repair

Score in Wound Healing From Surgery to 2 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 2 weeks post-laceration repair

Score in Wound Healing From Surgery 6 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 6 weeks post-laceration repair

Score in Wound Healing From Surgery 12 Weeks Follow-up as Measured Using the Patient and Observer Scar Assessment Scale (POSAS)-Observer Portion

Timeframe: 12 weeks post-laceration repair