Nutrition and Exercise Prehabilitation to Reduce Morbidity Following Major Liver Surgery in Sarcopenic Patients

Inclusion Criteria: * Age \>18. * Sarcopenic patients diagnosed by both qualitative and quantitative analysis. * Patients with primary or secondary liver malignancies. * Patients undergoing major liver resections intended as 3 or more contiguous segments * Patients undergoing open, laparoscopic, or robotic resections. Exclusion Criteria: * Minor liver resections intended as less than 3 contiguous segments. * Patients with intrahepatic, hilar, or extrahepatic cholangiocarcinomas. * Patients with liver tumors for whom 6 weeks interval from diagnosis to surgery could not be waited (i.e., large HCCs on healthy livers not requiring preoperative portal vein occlusion, CRLM without preoperative administration of anti-VEGF drug who therefore do not require 6 weeks of chemotherapy washout) * Patients with benign liver lesions. * Patients undergoing extrahepatic liver resections. * Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) procedure. * Patients with physical disabilities, unable to exercise. * Patients with inadequate kidney function.