The purpose of this study is to investigating the effect of Umbilical Cord Mesenchymal Stem Cell (UC-MSCs) and secretomes to insulin resistance in Polycystic Ovary Syndrome (PCOS) patients. This study has 4 arms namely UC-MSCs treatment, secretomes treatment, UC-MSCs and secretomes treatment, and control.
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Blood serum sample
Timeframe: Follicular phase on day 10-12
Free Androgen index (FAI)
Timeframe: Follicular phase on day 10-12
Insulin, Glucose Plasma, and Insulin Resistance
Timeframe: Follicular phase on day 10-12
Sex Hormone Binding Globulin (SHBG) and Anti-Mullerian Hormone (AMH)
Timeframe: Follicular phase on day 10-12, and 1,3,6 months after stem cells
Leptin and Adiponectine Profile
Timeframe: 1,3,6 months after stem cells
TNFα, IL-1 β, IL-6, IL-10 Profile
Timeframe: 1,3,6 months after stem cells