CompletedNot Applicable

A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step

Egypt202 participantsStarted 2014-06-01

Plain-language summary

Purpose: This study determined the incidence of burst abdomen recurrent (BAR), incisional hernia(IH), and surgical site occurrence (SSO) following burst abdomen surgical treatment after abdominal midline incisions using a posterior component separation(CS) technique with transversus abdominis muscle release (TAR) reinforced by retro-muscular mesh technique. Methods: Between June 2014 and April 2018, 202 patients with grade IA BA (Björck's first classification) were treated in a prospective multiple-center cohort study.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BA Grade IA according to Björck's initial classification following midline laparotomy from various departments, * ≥ 18 years * both sex * emergency or elective surgery Exclusion Criteria: * BA grade 1B,2,3, and 4 according to Björck's initial classification, * \< 18 years, * primary laparotomy performed through a non-midline incision, open abdomen, * if another laparotomy had been performed between the surgery for BA and the end of the follow-up period, * concomitant intra-abdominal surgery, abdominal complications during BA surgery, * adherent bowel to the defect edge that cannot be separated, * patients lost during follow up, * presence of intra-abdominal contamination that cannot be controlled radiologically, * history of previous BA repair, * stoma exteriorized from the midline primary wound, * temporarily wound closure techniques, * prior abdominal surgeries other than operation resulted in BA, * prior abdominal wall hernia repair with or without mesh, * history of collagen diseases

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

recurrent burst abdomen

Timeframe: 3.5 years

incisional hernia

Timeframe: 3.5 years

Trial details

NCT IDNCT05278117

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2018-04-01

View on ClinicalTrials.gov More Abdominal Wall Defect trials