ZOE METHOD Study: Comparing Personalized vs. Generalized Nutrition Guidelines

Inclusion Criteria: * Aged 40-70 years * Any sex * Waist circumference greater than ethnic- and sex-specific 25th percentile values: Male * Hispanic \> 96.3cm * Asian \> 87.3cm * Black \> 92.7cm * White \> 96.9cm Female * Hispanic \> 90.7cm * Asian \> 80.9cm * Black \> 92.9cm * White \> 88.3cm * Fruit and vegetable intake below 450g/day (equivalent to 3 cups/day) * Willing to comply with study protocol * Live in the continental US, Hawaii or Alaska, and not in New York State (due to governmental regulations pertaining to dried blood spot testing). * Do not meet any of the exclusion criteria Exclusion Criteria: * Have taken part in the ZOE product or any PREDICT study beforehand. * Are unable to read and write in English, as the ZOE app is only available in English. * Do not complete the first Quest visit successfully * Have an iOS/Android device not compatible with app * Use medications affecting lipids (lipid lowering drugs e.g statins, anti-diabetic medications, e.g metformin and insulin), supplements including fish oil (unless willing to safely come off these for 4 weeks before the start of the study, and for the duration of study); * Have ongoing inflammatory disease e.g rheumatoid arthritis, systemic lupus erythematosus, polymyalgia and other connective tissue diseases. * Have had cancer in the last three years, excluding skin cancer. * Have chronic gastrointestinal disorders including inflammatory bowel disease (IBD) or Celiac disease (gluten allergy), but…