Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Inclusion Criteria: * Subject with age ≥19 years and acute myocardial infarction * Rise and/or fall of cardiac troponin with one level \>99 percentile plus ischemic signs/symptoms * Subject with non-obstructive coronary arteries * \<50% diameter stenosis or * fractional flow reserve (FFR) \>0.80 ③ Subject without previous history of coronary artery disease * Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment Exclusion Criteria: * Subject with obstructive coronary arteries * Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies. * Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy \<1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent