CompletedPhase 3

Effect of Intracameral Steroids During Phacoemulsification on the Cornea

Egypt69 participantsStarted 2019-06-16

Plain-language summary

Prospective, interventional case control study. Sixty-nine eyes were randomized into 3 groups, 23 eyes each : 2groups received intracameral dexamethasone and triamcinolone (TA) respectively, while controls didn't receive any intraoperative steroids. Intracameral steroids at the conclusion of phacoemulsification significantly improved corneal edema and spared corneal endothelium.

Who can participate

Age range50 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Cataract grades 2 to 5 nuclear cataract (LOCS III scale) * uneventful phacoemulsification operation Exclusion Criteria: * extremely hard cataract grade 6 nuclear cataract (LOCS III scale) * soft cataract * subluxated lenses or zonular dehiscence * associated ocular pathology such as glaucoma * any signs of uveitis * trauma * retinal detachment * vitrectomized or silicone filled eyes * corneal disease such as Fuch's dystrophy, corneal opacity * previous refractive corneal surgery * Cases that developed ruptured posterior capsule and vitreous loss * those lost to follow up were excluded and randomly replaced by the next chronological patient

What they're measuring

Corneal edema

Timeframe: First day postoperative

Central corneal thickness (CCT)

Timeframe: Three months

Endothelial cell loss

Timeframe: Three months

Trial details

NCT IDNCT05271058

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-06-16

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