Neuraceq™ PET for Detection of Brain Changes in Young Athletes Post-concussion (NCT05270083) | Clinical Trial Compass
CompletedNot Applicable
Neuraceq™ PET for Detection of Brain Changes in Young Athletes Post-concussion
United States15 participantsStarted 2017-07-13
Plain-language summary
The purpose of the study is to learn if Neuraceq™ (Florbetaben F 18 Injection) PET can detect changes in the brains of young athletes who sustained one or more concussions with or without persistent cognitive complaints at least 5 years after injury.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18-40 years of age
* A minimum of 1 concussion prior to study entry
* A minimum of one year post first concussion
* mTBI as defined by the American Congress of Rehabilitative Medicine
* Participants in Cohort A must have either subjective or objective evidence of persistent cognitive deficits
Exclusion Criteria:
* Impaired decision-making capacity, i.e. inability to provide informed consent
* Pregnancy
* History of other neurologic disorders (e.g., epilepsy, cerebrovascular disease, neurodegenerative disorders, intellectual disability)
* Significant systemic medical illness
* Current DSM-IV Axis I diagnosis of psychiatric illness
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Neuraceq™ PET Imaging
Timeframe: Up to 90 minutes after injection
2
Cognitive Assessment_1
Timeframe: within 24 hours of [F-18]Florbetaben PET imaging
3
Cognitive Assessment_2
Timeframe: within 24 hours of [F-18]Florbetaben PET imaging