Lactobacillus-containing Cultured Milk Drink Alleviates Depression Score Among Adults With Irritable Bowel Syndrome

Inclusion Criteria: * Aged 18 to 65 years old, * Meet ROME IV criteria for irritable bowel syndrome, * Consented to participate in the study. Exclusion Criteria: * Lactose intolerance, * Gastrointestinal disorders such as inflammatory bowel diseases, liver diseases, pancreatic diseases or malignancies, * Any neurological diseases or malignancies, * Pregnant and lactating mothers, * Any metabolic diseases such as hypertension, hypercholesterolaemia, diabetes mellitus, hyper- and hypothyroidism. * Known psychiatric diagnoses or/and consume psychotropic drugs, * Ongoing electroconvulsive therapy (ECT), * Consumption of antibiotics, probiotics, prebiotics, symbiotics products, laxatives, antispasmodics, and/or anticholinergics who refuse to consent for participation.