CompletedNot Applicable

Influencing Factors of the Corneal Endothelial Cell Loss

France154 participantsStarted 2022-05-04

Plain-language summary

This is a multi-center cohort study with prognostic aims to identify factors associated with endothelial cell loss during cataract surgery. Patients will have their endothelial density measured by specular microscopy preoperatively, at 1 month and at 3 months after surgery. The rest of their management will be in line with standard practice.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing cataract surgery * Visual acuity monoyer scale \<8/10e (\> +0.2 logMar) * Nuclear, cortical and posterior subcapsular cataract with normal density to severe in the LOCSIII classification * Covered by the social security scheme * Have given their oral agreement Exclusion Criteria: * Corneal disease: keratitis, dystrophy or corneal degeneration * Any disease of the anterior segment * Low preoperative endothelial cell density \<1000 c/mm² * Pregnancy, lactation * Risk factors for surgical per-operative complication * Uncontrolled ocular pressure * Combined surgery (cataract with corneal graft, cataract with glaucoma surgery, cataract with vitrectomy, ....) * Under legal protection

What they're measuring

Postoperative endothelial cell loss

Timeframe: Month 3

Trial details

NCT IDNCT05265832

SponsorCentre Hospitalier Régional Metz-Thionville

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-17

View on ClinicalTrials.gov More Cataract trials