CompletedNot Applicable

Keto Drinks as a Meal Primer in Patients With Type 2 Diabetes

Denmark14 participantsStarted 2022-01-01

Plain-language summary

The main objective of this clinical trial is to study the effects of orally administered ketone drinks containing the ketone body, 3-hydroxybutyrate (3-OHB), just before a meal in patients with type 2 diabetes. Moreover the investigators will compare the effects of two different ketone drinks. The hypothesis is: 3-OHB as a pre-meal may: * Lower postprandial blood glucose and lipids. * Mediate release of intestinal hormones and affect gastric emptying. * Affect appetite and other subjective measures related to food intake. The effects of 3-OHB as a pre-meal will be investigated by blood samples, isotopic tracers examinations, paracetamol test, questionnaires and meal test.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Type 2 diabetes diagnosis, metformin treated or dietary treated * HbA1C \< 80 mmol/mol * 25 \< BMI \< 35 * Written consent Exclusion Criteria: * Severe comorbidity * Treatment with insulin, GLP-1 analogues, SGLT-2-inhibitors or sulfonylureas * Specific diets, e.g. ketogenic diet * PI finds the patient not fit (e.g. mental illness, too nervous, unacceptable screening blood tests or other)

What they're measuring

Postprandial P-glucose

Timeframe: 3 hours

Trial details

NCT IDNCT05263401

SponsorUniversity of Aarhus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-30

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