Clinical Efficacy of Exosome in Degenerative Meniscal Injury

Inclusion Criteria: * Accepting the Informed Consent Form * Degenerative meniscus damage grade 1, 2 or 3 on MRI in both right and left knees, and also the patient does not want surgical treatment * Patients with the same degenerative meniscus grade in both knees * Patients with ongoing pain * Patients without a history of malignancy * Absence of signs of unstable meniscus tear such as snagging or locking * Patients with stage 0, 1 or 2 gonarthrosis according to Kellgren-Lawrence gonarthrosis staging * Patients without lower extremity malalignment Exclusion Criteria: * Patients whose treatment method was explained and who did not accept the method * Patients outside the working-age range * Congenital lesion * Patients requiring surgical treatment (e.g. bucket handle tear and locked knee) * Active inflammatory or connective tissue disease is thought to affect the patient's pain (eg lupus, rheumatoid arthritis, fibromyalgia) * Local or systemic infection * Pregnant or breastfeeding women * Active endocrine disorder that may affect the assessment of patient's pain (eg, hypothyroidism, diabetes) * Active neurological disorder that may affect the assessment of the patient's pain (eg, peripheral neuropathy, multiple sclerosis) * Active heart disease * Presence of a pacemaker * Conditions where MR-I is contraindicated * Patients with stage 3 or 4 gonarthrosis according to Kellgren-Lawrence gonarthrosis staging * Patients with lower extremity malalignment * Patients with signs of u…