Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout

Inclusion Criteria: * History of gout * at least 1 measurable tophus on the hands/wrists and/or feet/ankles ≥ 5 mm and ≤ 30 mm in the longest diameter. * Patients who are NOT on approved ULT must have sUA \> 7 mg/dL * Patients who are on medically appropriate ULT must have sUA \> 6 mg/dL * Estimated Glomerular Filtration Rate (eGFR) ≥ 45 mL/min/1.73m2 Exclusion Criteria: * Malignancy within 5 years, except for successfully treated basal or squamous cell carcinoma of the skin * Pregnant or breastfeeding * History of kidney stones