TerminatedPhase 2

Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy

Stopped: Investigator and study team chose to end study early.

United States56 participantsStarted 2022-04-21

Plain-language summary

The purpose of this study is to prospectively determine the effects of administering proton pump inhibitors (PPIs) following pancreaticoduodenectomy on postoperative outcomes. The findings of this study will help in avoiding the widespread use of PPIs during the immediate postoperative period following pancreatic surgery.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All consecutive patients who will undergo pancreaticoduodenectomy with gastric/biliary reconstruction performed as definitive management for a benign or malignant disease at Washington University/Barnes-Jewish Hospital. * At least 18 years of age. * Ability to understand and willingness to sign an IRB approved written informed consent document. Exclusion Criteria: * \<18 years of age

What they're measuring

Number of Participants With Delayed Gastric Emptying as Measured by the International Study Group of Pancreatic Surgery (ISGPS) Criteria

Timeframe: Through 90 days after surgery

Number of Participants With Delayed Gastric Emptying as Measured by Modified Accordion Grading System (MAGS)

Timeframe: Through 90 days after surgery

Trial details

NCT IDNCT05251233

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-29

Results submitted2025-03-31

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