Argon Plasma Coagulation and Clip for the Prophylaxis of Post-polypectomy Bleeding After Hot Snar… (NCT05250518) | Clinical Trial Compass
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Argon Plasma Coagulation and Clip for the Prophylaxis of Post-polypectomy Bleeding After Hot Snare Polypectomy
China1,017 participantsStarted 2022-03
Plain-language summary
Discuss the efficacy and safety of argon plasma coagulation （APC）in comparison with clip closure for preventing colorectal post-procedure bleeding（PPB） after hot snare polypectomy（HSP）; analyze the risk factors and the cost-effectiveness of bleeding prophylaxis strategies with Decision Tree Analytical Method.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. age\>18 years
✓. the diagnosis of colorectal polyps is clear（Paris Ip or â… sp）
✓. head diameter≥ 10 mm
✓. HSP indications were met and no contraindications were found
✓. patients (or the legal representative/guardian) with informed consent
Exclusion criteria
✕. ASA Grade Ⅲ or above, or end-stage disease of major organs (such as malignancy, heart failure, chronic obstructive pulmonary disease, end-stage renal disease and so on)
✕. use antiplatelet drugs within 7 days before the operation, anticoagulant drugs within 5 days, and/or blood products within 30 days after the operation
✕. there were other lesions in the resection site of the included polyps affecting this study, or the intestinal preparation was insufficient
✕. incomplete closure of clips (complete closure: spacing between adjacent clips \< 1cm)
✕. APC is used for polypectomy or intraoperative hemostasis, rather than preventing PPB
✕. surgical treatment, vascular intervention, or blood products were used during the operation