UnknownPhase 2/3

Pronase Granules in Gastric Cleaning

China290 participantsStarted 2021-02-24

Plain-language summary

Magnetically controlled capsule endoscopy (MCE) is now widely used all over the world. However, the standard gastric preparation method by dimethicone we used clinically still has mucus at the bottom of the stomach. In this study, we aimed to determine whether pronase granules is helpful to improve the cleanliness of gastric mucosa in MCE.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age ≥ 18 years old.
✓. Those who underwent upper gastrointestinal and small intestinal mucosal examination under magnetically controlled capsule endoscopy at Shanghai Changhai Hospital and Chinese People's Liberation Army General Hospital after January 2020.
✓. Able to provide informed consent.

Exclusion criteria

✕. dysphagia or symptoms of gastric outlet obstruction, suspected or known intestinal stenosis, overt gastrointestinal bleeding, history of upper gastrointestinal surgery or abdominal surgery altering gastrointestinal anatomy, or post-abdominal radiation;
✕. congestive heart failure, renal insufficiency, use of anticoagulant medication,
✕. implanted metallic devices such as pacemakers, defibrillators, artificial heart valves or joint prostheses (although the low magnetic field used technically should not interfere with such devices);
✕. pregnancy;
✕. currently participating in another clinical study.
✕. Patients who fail to follow the prescribed procedures for magnetically controlled capsule endoscopy;
✕. Patients who only undergo gastric examination under magnetically controlled capsule endoscopy;
✕. Patients who only undergo small bowel examination under magnetic control capsule endoscopy;

What they're measuring

Gastric Cleanliness Score (GCS)

Timeframe: 2 weeks

Trial details

NCT IDNCT05249933

SponsorChanghai Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-20

Contact for this trial

Zhuan Liao

021-31161024 zhuanleo@126.com

View on ClinicalTrials.gov More Gastric Disease trials