TerminatedPhase 2/3

Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?

Stopped: Inability to obtain recruitment levels needed for study to continue.

United States11 participantsStarted 2022-04-13

Plain-language summary

This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.

Who can participate

Age range18 Years – 85 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * women with biopsy proven lichen sclerosus and significant symptoms based on Skindex-29 scores \>21 Exclusion Criteria: * prior vaginal mesh or pelvic radiation * active genital infection * Current or past gynecologic malignancy

What they're measuring

Change in Skindex-29 Score

Timeframe: Completed by the subject at baseline and 6 months.

Trial details

NCT IDNCT05243563

SponsorUniversity of South Alabama

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-03

Results submitted2025-06-03

View on ClinicalTrials.gov More Vulvar Lichen Sclerosus trials