Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)

Inclusion Criteria: * Age 2-75 years * patients with existing clinical diagnosis or suspected FH * known genetic mutation of FH * patients with an initial (pretreatment) LDL level \>190 mg/dL or total cholesterol \>300 mg/dL (age \>19 years) or LDL-c \> 160mg/dL or total cholesterol \>260 mg/dL in children age 2-19 years * patients currently taking a lipid-lowering medication and have an LDL \>124 mg/dL or total cholesterol \>195 mg/dL * capable of providing informed consent * Patients should reside in Minnesota, Wisconsin or North Dakota. Exclusion Criteria: * Lack of research authorization * unable to provide informed consent (including non-English speaking individuals) * known medical condition other than FH that is thought to contribute to hyperlipidemia (i.e., untreated hypothyroidism, nephrotic syndrome, cholestasis hypopituitarism) * Pregnant women and prisoners will also be excluded.