CompletedPhase 4

Lidocaine VS Hemodynamic, Metabolic and Hormonal Response

Poland132 participantsStarted 2022-03-12

Plain-language summary

Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management in adults. In children population promising but limited evidence is available. The study has been planned to evaluate the efficacy of continuous intravenous infusion of lidocaine in alleviation of hemodynamic reaction to tracheal intubation, as well as metabolic and hormonal response to laparoscopic procedure in children.

Who can participate

Age range18 Months – 18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA physical status class 1E, 2E, 3E; * Patients undergoing laparoscopic appendectomy. Exclusion Criteria: * Allergy to local anesthetics or contraindications for the use of lidocaine; * ASA physical status class 4E or higher; * Severe cardiovascular disease; * Preoperative bradycardia; * Preoperative atrioventricular block; * Renal failure; * Chronic treatment with analgesics; * Legal guardians' refusal.

What they're measuring

Hemodynamic reaction to tracheal intubation

Timeframe: Before intubation - immediately after intubation.

Trial details

NCT IDNCT05238506

SponsorMedical University of Warsaw

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-08

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