CompletedNot Applicable

Evaluation of the Impact of Reduced Immunosuppression

United States100 participantsStarted 2021-10-19

Plain-language summary

Graft-versus-host disease (GVHD) is a life-threatening complication of transplantation. It occurs when the donor graft contains immunologically competent T-cells that recognize the recipient as foreign.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ≥ 18 years * Received OLT or Combined Kidney-Liver Transplant(CKLT) during study period Exclusion Criteria: * Recipients requiring re-transplant within one month post-transplant * Recipients who died of a cause other than GVHD within one month post-transplant

What they're measuring

Incidence of GVHD at one year post-transplant

Timeframe: September 12, 2004 to June 30, 2020

Graft rejection at one year post-transplant

Timeframe: September 12, 2004 to June 30, 2020

Trial details

NCT IDNCT05238155

SponsorMethodist Health System

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-07-29

View on ClinicalTrials.gov More Graft Vs Host Disease trials