TerminatedNot Applicable

Comparing the Efficacy of Visible Light-Ultraviolet A1 Light Versus Narrowband-Ultraviolet B on Generalized Vitiligo

Stopped: only one subject enrolled, decided to re-evaluate protocol design

United States1 participantsStarted 2018-02-26

Plain-language summary

As part of this study, you may have a procedure called phototherapy which involves either VL-UVA or NB-UVB irradiation. NB-UVB phototherapy is not experimental in vitiligo, but use of VL-UVA1 phototherapy in vitiligo is. The purpose of this pilot study is to determine whether VL-UVA1 or NB-UVB phototherapy more efficiently induces repigmentation in patients with generalized vitiligo.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects ≥ 18 years of age with a diagnosis of generalized vitiligo * Subjects on a stable topical/oral regimen for the past 3 months and continuing on a stable regimen * Subjects able to understand the requirements of the study * Subjects able and willing to sign informed consent Exclusion Criteria: * Subjects on photosensitizing medications * Subjects receiving any concurrent phototherapy * Subjects who plan to use tanning parlors or expose themselves to excess sunlight * Subjects with known photosensitivity disorder * Subjects with apparent phototoxicity * Subjects with unstable vitiligo * Subjects currently using bleaching agents * Subjects who are pregnant, lactating, or planning on becoming pregnant * Subjects who in the opinion of the investigator/sub-investigator, are not appropriate candidates for this study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in depigmentation of vitiligo lesion

Timeframe: 13 measurements over 26 visits

Change in melanin content of vitiligo lesion

Timeframe: 13 measurements over 26 visits

Trial details

NCT IDNCT05238077

SponsorHenry Ford Health System

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05-01

View on ClinicalTrials.gov More Generalized Vitiligo trials