CompletedPhase 4

The Influence of Tramadol on Platelet Function

Austria33 participantsStarted 2022-01-26

Plain-language summary

The aim of this ex-vivo study is to quantify the effect of tramadol on platelet aggregation.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18y and older, healthy volunteers Exclusion Criteria: * Age \< 18 years * Pregnant women * History of addiction (especially opiate abuse) * Pre-existing general addictive disease * Ongoing pain therapy with opiates * Taking antidepressants (SNRI, SSRI) * History of thrombocytopathy or coagulation disorders * Therapy with drugs that influence thrombocyte function (ASS, clopidogrel, prasugrel, ticagrelor or similar) * Known intolerance to opiates

What they're measuring

Procoagulant effect on platelet function demonstrated by optical aggregometry (LTA) on whole blood.

Timeframe: up to 4 hours

Trial details

NCT IDNCT05237492

SponsorMedical University of Graz

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-15

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