Exercise Capacity and Physical Activity Level in Prolactinoma Patients (NCT05236829) | Clinical Trial Compass
CompletedNot Applicable
Exercise Capacity and Physical Activity Level in Prolactinoma Patients
Turkey (Türkiye)38 participantsStarted 2021-06-16
Plain-language summary
Prolactinoma, one of the most common pituitary adenomas, is an adenoma that causes excessive prolactin (PRL) secretion. An increase in prolactin level can cause weakness, decrease in muscle mass and fatigue. It is not known in detail to what extent it affects quality of life, functional exercise capacity, cardiovascular disease risk factors, physical activity level, fatigue and sleep quality in prolactinoma patients. It is aimed to compare how much exercise capacity, physical activity level, sleep quality, perception of fatigue and quality of life of prolactinoma patients are affected compared to healthy individuals and to examine the factors associated with exercise capacity in prolactinoma patients.
Who can participate
Age range
18 Years – 55 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria of patients:
* Being between the ages of 18-55
* Woman
* Being diagnosed with prolactinoma
* Volunteering to participate in the study
Exclusion Criteria of the patients :
* Patients with neurological, cognitive or orthopedic disease that will affect the measurements
* Patients with severe respiratory disease (FEV1 \< 35%; FVC \< 50%)
* Presence of acute infection
* Presence of malignancy
* Presence of dementia
* Patients who have had a cardiovascular event in the last 6 months
* Less than 50% of the ejection fraction
* Patients with uncontrolled hypertension
* Individuals with a diagnosis of uncontrolled diabetes mellitus will not be included in the study.
Healthy group inclusion criteria:
* Being between the ages of 18-55
* Woman
* Not being diagnosed with any pituitary adenoma
* Volunteering to participate in the study
Healthy group exclusion criteria:
* Cases with neurological, cognitive or orthopedic diseases that will affect the measurements
* Cases with severe respiratory disease (FEV1 \< 35%; FVC \< 50%)
* Presence of acute infection
* Presence of malignancy
* Presence of dementia
* Cases who have had a cardiovascular event in the last 6 months
* Less than 50% of the ejection fraction
* Patients with uncontrolled hypertension
* Cases with uncontrolled diabetes mellitus diagnosis will not be included in the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.