Active — Not RecruitingNot Applicable

Auricular Vagus Stimulation in Obesity

Russia131 participantsStarted 2022-04-04

Plain-language summary

Transcutaneous vagus nerve stimulation (TENS) involves stimulation of the left and/or right auricular branch of the vagus nerve with low-frequency electrical impulses. In recent years, the possibilities of using this technology in chronic conditions characterized by immune and metabolic dysregulation have been studied. The aim of this study is to investigate the effectiveness of TENS in reducing weight and improving quality of life in patients with various degrees of obesity.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adult patients with grade 1-2 nutritional obesity who are willing and able to give informed written consent to participate in the study, are on sinus rhythm and are not taking any antiarrhythmic drugs, including beta-blockers. Exclusion Criteria: * Cardiac arrhythmias: bradyarrhythmias, Atrioventricular blockades of any degree; * Taking beta blockers; * The endocrine nature of obesity; * Expected technical difficulties when using the device on the part of the patient; * Pregnant or plan on becoming pregnant or breastfeeding during the study period; * Presence of an electrically, magnetically or mechanically activated implant, an intracerebral vascular clip, or any other electrically sensitive support system.

What they're measuring

Percentage of body fat

Timeframe: 6-month follow-up

Body Mass Index

Timeframe: 6-month follow-up

Waist circumference

Timeframe: 6-month follow-up

Trial details

NCT IDNCT05230628

SponsorNational Medical Research Center for Therapy and Preventive Medicine

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-01-31

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