Opiate Sparing Protocol Randomized Controlled Trial in Open Distal Radius Fracture Repair

Inclusion Criteria: * Open reduction internal fixation surgery at Campbell Clinic Surgery Center * Body Mass Index less than or equal to 45 * Fluent in verbal and written English Exclusion Criteria: * Known sensitivity to medications in either protocol * Renal disease by medical history * Concomitant ipsilateral upper extremity injury or condition other than wrist * Chronic pain syndrome * Consumption of ten consecutive day so opioid use in the previous 90 days * Worker's compensation * Women who are pregnant, planning to become pregnant, or are breastfeeding * Takes either angiotensin-converting enzyme inhibitor or angiotensin II receptor blockers for hypertension