RecruitingNot Applicable

Immune Responses to Gluten

United States400 participantsStarted 2023-01-15

Plain-language summary

This is a study of immune responses after eating gluten powder in people with celiac disease and healthy controls.

Age range2 Years – 101 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. Pregnancy
✕. Wheat allergy
✕. Type 1 diabetes
✕. BMI z-score \< -2
✕. History of more than minimal symptoms following gluten exposure on a gluten-free diet
✕. Comorbid condition that in the opinion of the investigator would interfere with study participation or would confound study results

Change in serum interleukin-2 (IL-2) level from baseline to 4 hours after a single oral dose of gluten

Timeframe: Baseline, 4 hours

NCT IDNCT05209568

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-09-30

Jocelyn A Silvester, MD, PhD