CompletedNot Applicable

Comparison of the Efficacy of Platelet-rich Fibrin and Connective Tissue Graft in Interdental Papilla Reconstruction

Turkey (Türkiye)55 participantsStarted 2018-09-05

Plain-language summary

Aim: To evaluate the efficacy of platelet-rich fibrin (PRF) or connective tissue graft (CTG) in papilla reconstruction (PR) with semilunar incision (SI) technique. Materials and Methods: A total of 55 sites (27 CTG and 28 PRF) from 20 patients who underwent PR with either PRF or CTG placed with SI in the maxillary anterior region were included in the study. Baseline (BL) and follow-up (T1( first month), T3 (third month), T6 (sixth month)) clinical data including periodontal evaluations (gingival index (GI), plaque index (PI), papillary bleeding index, pocket depth (PD), keratinized tissue width (KTW), gingival recession), papilla-associated recordings (alveolar crest-interdental contact point (AC-IC), alveolar crest-papilla tip (AC-PT), papilla tip-interdental contact point (PT-IC), papilla height loss (PHL), interdental tissue stroke (ITS) and papilla presence index (PPI)) and patient satisfaction were analyzed.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All selected patients had consent for using their data. * The data of the patients who underwent PR surgery by one of the authors (S.O.B.) using SI with either PRF or CTG in the maxillary anterior teeth having contact points, * at least 2 mm keratinized tissue width (KTW) with probing depth (PD)≤ 3 mm adjacent to the open embrasure were included. * It was ensured that all baseline (BL) and follow-up data were available and all patients received a comprehensive phase I periodontal treatment prior to the PR procedure. Exclusion Criteria: * the patients with systemic problems, * having medications known to influence the periodontium * Using tobacco/alcohol * The relevant regions did not have endodontic problems/needs, caries and history of periodontal surgery.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: baseline

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T1:1st month

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T3:3rd month

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T6: 6th month

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: baseline

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: T1:1st month

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: T3:3rd month

Alveolar crest-Papilla tip (AC-PT mm)

Trial details

NCT IDNCT05207696

SponsorHacettepe University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-11-01

View on ClinicalTrials.gov More To Evaluate the Efficacy of Platelet-rich Fibrin in Papilla Reconstruction trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: baseline

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T1:1st month

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T3:3rd month

Alveolar crest-Interdental contact point (AC-IC mm)

Timeframe: T6: 6th month

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: baseline

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: T1:1st month

Alveolar crest-Papilla tip (AC-PT mm)

Timeframe: T3:3rd month

Alveolar crest-Papilla tip (AC-PT mm)