Effects of Different Moderate-intensity Exercise Methods on Health in the Elderly (NCT05207501) | Clinical Trial Compass
CompletedNot Applicable
Effects of Different Moderate-intensity Exercise Methods on Health in the Elderly
Switzerland60 participantsStarted 2022-09-01
Plain-language summary
Aging is linked to a higher risk of cardiovascular disease. Physical exercise is recognized as an excellent strategy to prevent cardiovascular diseases and cognitive aspects, generating healthier elderly people. The beneficial effects of physical training seem to be greater when performed:
* In hypoxic conditions (i.e. when the amount of oxygen in the air is decreased as at altitude).
* With intermittent blood flow restriction (by inflating pneumatic cuffs around the thighs to a pressure that restricts blood flow). This equipment is harmless.
* With eccentric training (resisting against the movement of the pedal of a bicycle rather than pushing it).
The purpose of this study is then to evaluate whether moderate intensity intermittent training can induce similar or greater effects on cardiovascular health when combined with intermittent hypoxia, intermittent blood flow restriction or eccentric training.
Who can participate
Age range
65 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. to be aged between 65 and 75 years old
. not involved in regular physical activities for at least 6 months (i.e., doing no physical exercise over twice per week);
. free of injuries as well as cardiovascular and respiratory disorders or central nervous system disease or receiving β-blocker medication;
. not using dietary supplements, smoking or drugs which interfere with the measurements;
. not using creatine supplementation, anabolic steroids, drugs, or medication with potential effects on physical performance;
. to have body index mass between 20 and 30 kg/m²;
. not to live above 800m of altitude;
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Blood pressure [mmHg]
Timeframe: 4 weeks
2
Baroreflex sensitivity
Timeframe: 4 weeks
3
Flow-mediated dilation
Timeframe: 4 weeks
4
Heart rate variability
Timeframe: 4 weeks
5
6-Minute Cycle Test [km]
Timeframe: 4 weeks
6
Knee flexion and extension isokinetic strength [N]