Healthy Early Life Moments in Singapore (NCT05207059) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Healthy Early Life Moments in Singapore
Singapore500 participantsStarted 2022-03-18
Plain-language summary
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health, among overweight and obese women.
Who can participate
Age range
21 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Women aged 21-40 years
. BMI 25-40 kg/m2
. Intention to reside in Singapore for the next 4 years
. Chinese, Malay, Indian or any combination of these 3 ethnic groups
. Planning to conceive within 1 year
. Able to understand English
. Able to provide written, informed consent
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pregnancy rate
Timeframe: Up to 12 months
2
Maternal metabolic health
Timeframe: Up to 40 months, between preconception, pregnancy and 18 months postpartum
3
Maternal mental health
Timeframe: Up to 26 months, between preconception, pregnancy and 4 months postpartum
. On any anticonvulsant medication in the past 1 month
. On any oral steroid in the past 1 month (e.g. Prednisolone, Prednisone, Deltasone, Prelone, Methyl Prednisolone, Medrol, Hydrocortisone, Cortef, Dexamethasone, Decadron)
. On any oral, implanted contraception or intrauterine contraceptive device (IUCD) in situ in the past 1 month
. On any fertility medication (e.g. hormones injection, IVF treatments) other than Clomiphene/ Letrozole in the past 1 month
. On HIV or Hepatitis B or C medication in the past 1 month.