Histamine as a Molecular Transducer of Adaptation to Exercise (NCT05206227) | Clinical Trial Compass
Active — Not RecruitingEarly Phase 1
Histamine as a Molecular Transducer of Adaptation to Exercise
United States80 participantsStarted 2021-07-28
Plain-language summary
This study is investigating the role of histamine in generating adaptation to exercise
Who can participate
Age range18 Years – 40 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 -40
Exclusion Criteria:
* Systolic ≥ 120
* Diastolic ≥ 80
* Body mass index (BMI) ˃ 28 kg/m2
* Prior diagnosis of cardiovascular disease, diabetes, autonomic disorders, or asthma
* Smoking or nicotine use
* Ongoing medical therapy (other than birth control)
* Ongoing use of over-the-counter or prescription antihistamines
* Allergies or hypersensitivities to drugs, local anesthetics, skin disinfectants, adhesives, or latex
* Pregnant, breastfeeding subjects, or planning to become pregnant in the next 12 months
* Mobility restrictions that interfere with physical activity
* High physical activity based on International Physical Activity Questionaire (IPAQ1)
* Non-English speaking