CompletedNot Applicable

Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn's Disease: A Pilot Study

United States27 participantsStarted 2022-03-14

Plain-language summary

This study aims to further define and characterize imaging findings of possible sacroiliitis in Crohn's Disease patients by recalling subjects who had findings of possible sacroiliitis on prior MRE and assess the natural history and outcome of these cases by using standard magnetic resonance imaging (MRI) and x-ray of the sacroiliac joints.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Evidence of sacroiliitis on earlier standard of care MRE between 2014 and 2018. * Confirmed diagnosis of Crohn's Disease * Known HLA-B27 status at time of enrollment and most recent clinical ESR and CRP results from chart (from day of visit or within past 4 weeks of study visit) * Adults \>18 years of age Exclusion Criteria: * History of other inflammatory arthritis (e.g. rheumatoid arthritis, systemic lupus erythematosus, gout). * Contraindication to MRI. * History of malignancy \<5 years in remission, (except for non-melanomatous skin cancer). * Inability to comply with study protocol. * Critically ill patients. * Pregnant patients. * Non-English speaking patients (as the questionnaires used in this study are not validated in other languages)

What they're measuring

Significance of sacroiliitis features/lesions seen on Magnetic Resonance Enterography (MRE)

Timeframe: Intervention Visit 1 (Day 1)

Significance of sacroiliitis features/lesions seen on Magnetic Resonance Enterography (MRE)

Timeframe: Intervention Visit 1 (Day 1)

Trial details

NCT IDNCT05203926

SponsorNYU Langone Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-04

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