UnknownNot Applicable

Endothelial Changes in Pseudoexfoliation Syndrome

100 participantsStarted 2022-02-01

Plain-language summary

this study aimed to evaluate the corneal endothelial cell changes before and after phacoemulsification in pseudoexfoliative patients relative to healthy adults.

Who can participate

Age range

50 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patient age is above50 years.
. Patient with nuclear cataract grade II, III.
. Clear cornea with no evidence of endothelial disease.
. Endothelial cell density more than 1000\\mm2.
. Normal anterior chamber depth and dilatable pupil.
. No active ocular disease or inflammation.
. Pseudoexfoliative patients.

Exclusion criteria

. History of previous trauma, intraocular surgery or ocular surface infection in recent two weeks.
. Presence of any corneal opacity, endothelial disease, scarring or dystrophies.
. Pseudoexfoliative glaucoma.
. Patients age below 50 years.
. Endothelial cell count less than 1000\\mm2.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Study of corneal endothelial changes in pseudoexfoliation syndrome

Timeframe: Baseline

Trial details

NCT IDNCT05194891

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-02

Contact for this trial

Shymaa Ahmed, Doctor

+20 106 319 4646 shymaa.sabet@yahoo.com

View on ClinicalTrials.gov More Endothelial Cell Loss, Corneal trials